ABSTRACT. The present study aimed to evaluate the in vitro antimicrobial activity of pharmacologically important Adhatoda vasica plant extracts. Plant Adhatoda vasica L. Nees (Acanthaceae) commonly known as Malabar nut is an evergreen two – three m tall shrub, sometime used as. Adhatoda vasica (L.) (Acanthaceae) is used in the indigenous system of medicine in India. The alkaloid Vasicine was isolated from ethanolic extract of the .

Author: Akinris Brajora
Country: Andorra
Language: English (Spanish)
Genre: Finance
Published (Last): 21 August 2014
Pages: 481
PDF File Size: 9.41 Mb
ePub File Size: 8.10 Mb
ISBN: 469-4-89084-407-1
Downloads: 50278
Price: Free* [*Free Regsitration Required]
Uploader: Doushakar

Materials and Adhatoca 2. The spot turned orange red on spraying with Dragendorff’s reagent. Effect of Adhatoda vasica massage in pyorrhoea. Glossary of Indian Medicinal Plants.

Nature acts as a prominent anti,icrobial for new and novel therapeutics. Classical Uses of Medicinal Plants. The plant was identified by Dr. Indian Journal of Natural Products and Resources.

Asian Journal of Microbiology, Biotechnology & Environmental Sciences Paper

Then kf residue was crystallised from chloroform to get Vasicine acetate as colorless crystals m. Cytotoxicity of each sample was expressed as IC 50 value. Journal of Obstetrics and Gynaecology of India. Vasicine showed antimicrobial activity against S. International Journal of Cancer. Published online Jan Mobile phase A consisted of water with 0.


Abstract Adhatoda vasica L. The plant is used in the indigenous system of medicine in India and is a well-known expectorant in both Ayurvedic and Unani Systems of Medicine [ 45 ].

Ray of hope for cancer patients.

The physical and spectroscopic data were compared with those reported in the literature [ 2122 ]. The ethanol extract of A. The fraction was further purified and the compound Vasicine was isolated. Conflict of Interests The authors declare that there is no conflict of interests regarding the publication of this paper. International Journal of Green Pharmacy. Indian Journal of Microbiology. Shade dried and coarsely powdered leaves of A. HPLC analysis was carried out on a Waters Alliance separations module with photodiode array detector Waters, Vasicine acetate showed antimycobacterial activity [ 15 ].

The authors declare that there is no conflict of interests regarding the publication of this paper. aantimicrobial

Two mobile phases A and B were used at flow rate of 1. Evaluation of antioxidant activity of isoferulic acid in vitro. In the present communication we report the antimicrobial, antioxidant, and anticancer effects of Vasicine acetate acetylated from Vasicine obtained from A.


Antibacterial activity of adhatoda vasica leaf extract

Antibacterial and antifungal activities were carried out using disc diffusion method [ 16 ]. Vasicine acetate could be checked further in drug discovery programme. Minimum inhibitory concentration studies of the compounds were performed according to the standard reference methods for bacteria [ 17 ] and filamentous fungi [ 18 ].

HPLC chromatograms of the ethanol extract of the leaves of Adhatoda vasica. Conclusion Vasicine acetate was obtained by acetylation of Vasicine recovered from A. Sankar2 and K. The plant contains alkaloids such as Vasicine, vasicinone, deoxyvasicine, vasicol, adhatodinine, and vasicinol [ 12 ]. The worldwide threat of antimicrobial resistance.

B revised New Delhi, India: The antifungal agent Ketoconazole for fungi and antibacterial agent Streptomycin for bacteria were included in the assays as positive controls.